ABSTRACT
To evaluate the effect of local resection plus axillary dissection in the treatment of early breast cancer, 112 cases of early breast cancer were divided into 2 groups: quadrant resection plus axillary dissection group(66 cases) and Halsted′s method group(46 cases).Their survival rate, local recurrence rate, metastasis rate,cosmetic effect of breast were observed for a prolonged period. The results showed that the 3,5,8 year survival rates in the first group were respectively 97 0%,87 9% and 71 2%. The 3,5,8 year survival rates in the second group were respectively 97 8%,80 5%,76 1%. The rate of local recurrence was 6 1% in the first group and 4 3% in the second group.The metastasis rate of the first group was 16 7%,and that of the second group was 21 6%.In 83 8% of patients in the first group,the breasts retained a satisfactory cosmetic form.It suggested that similar to the Halsted's method,the quadrant resection plus axillary dissection method is an ideal method to treat early breast cancer.
ABSTRACT
Objective To evaluate the necessity, feasibility, accuracy and clinical value of sentinel lymph node (SLN) biopsy (SLNB) in early breast cancer. Methods In 32 cases with early breast cancer, sentinel lymph nodes identified by liposomes methylence blue mixture were excised for biopsy. The patients then received operations for breast cancer, including axillary lymph nodes dissection. SLN and avillary lymph nodes (ALN) were separately examined histopathologically. Results SLN was identified in 31 cases, success rate was 96.9%. In 9 of the 31 patients, SLN was positive for metastasis, in 22 of the 31 patients, SLN was negative for metastasis. In 10 of 32 patients, ALN was positive for metastasis, and in 22 of 32 patients, ALN was negative for metastasis. The sensitivity rate of SLNB was 90%, The accuracy rate of SLN was 93.8%, with a false negative rate of 10% and a false positive rate of zero. Conclusion The SLN biopsy can accurately predict the axillary metastasis for patients with breast cancer. Liposomes methylenc blue mixture tracing may increase the success rate of SLNB.